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Divergent effects of Porcupine and Wntless on WNT1 trafficking, secretion, and signaling

Loss-of-function studies have identified Porcupine (PORCN) and Wntless (WLS) as essential mediators of Wnt secretion and signaling. Whereas PORCN is thought to palmitoylate Wnt proteins, WLS is believed to transport palmitoylated Wnt proteins to the cell surface. However, little is known about how t...

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Dades bibliogràfiques
Publicat a:Exp Cell Res
Autors principals: Galli, Lisa M., Zebarjadi, Navid, Li, Lydia, Lingappa, Vishwanath R., Burrus, Laura W.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032901/
https://ncbi.nlm.nih.gov/pubmed/27492485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.07.028
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