Determination of the membrane topology of PORCN, an O-acyl transferase that modifies Wnt signalling proteins

Wnt gradients elicit distinct cellular responses, such as proliferation, specification, differentiation and survival in a dose-dependent manner. Porcupine (PORCN), a membrane-bound O-acyl transferase (MBOAT) that resides in the endoplasmic reticulum, catalyses the addition of monounsaturated palmita...

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Bibliografiska uppgifter
I publikationen:Open Biol
Huvudupphovsmän: Galli, Lisa M., Anderson, Marc O., Gabriel Fraley, J., Sanchez, Luis, Bueno, Raymund, Hernandez, David N., Maddox, Eva U., Lingappa, Vishwanath R., Burrus, Laura W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Royal Society 2021
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241489/
https://ncbi.nlm.nih.gov/pubmed/34186010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200400
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