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Determination of the membrane topology of PORCN, an O-acyl transferase that modifies Wnt signalling proteins
Wnt gradients elicit distinct cellular responses, such as proliferation, specification, differentiation and survival in a dose-dependent manner. Porcupine (PORCN), a membrane-bound O-acyl transferase (MBOAT) that resides in the endoplasmic reticulum, catalyses the addition of monounsaturated palmita...
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| Publicado no: | Open Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8241489/ https://ncbi.nlm.nih.gov/pubmed/34186010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200400 |
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