Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia()

Preclinical studies have suggested that the pancreatic tumor microenvironment both inhibits and promotes tumor development and growth. Here we establish the role of stromal fibroblasts during acinar-to-ductal metaplasia (ADM), an initiating event in pancreatic cancer formation. The transcription fac...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Pitarresi, Jason R., Liu, Xin, Sharma, Sudarshana M., Cuitiño, Maria C., Kladney, Raleigh D., Mace, Thomas A., Donohue, Sydney, Nayak, Sunayana G., Qu, Chunjing, Lee, James, Woelke, Sarah A., Trela, Stefan, LaPak, Kyle, Yu, Lianbo, McElroy, Joseph, Rosol, Thomas J., Shakya, Reena, Ludwig, Thomas, Lesinski, Gregory B., Fernandez, Soledad A., Konieczny, Stephen F., Leone, Gustavo, Wu, Jinghai, Ostrowski, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2016
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031867/
https://ncbi.nlm.nih.gov/pubmed/27659014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.07.006
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