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Plasticity of the Leishmania genome leading to gene copy number variations and drug resistance
Leishmania has a plastic genome, and drug pressure can select for gene copy number variation (CNV). CNVs can apply either to whole chromosomes, leading to aneuploidy, or to specific genomic regions. For the latter, the amplification of chromosomal regions occurs at the level of homologous direct or...
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| Publicado en: | F1000Res |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
F1000Research
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5031125/ https://ncbi.nlm.nih.gov/pubmed/27703673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.9218.1 |
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