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A VP22-Null HSV-1 Is Impaired in Inhibiting CD1d-Mediated Antigen Presentation

CD1d-restricted T (natural killer T [NKT]) cells are important for controlling a herpes simplex virus (HSV) infection. One of the mechanisms of immune evasion by HSV is to downregulate CD1d-mediated activation of NKT cells. VP22 is an HSV-1-encoded protein responsible for reorganizing the host cell&...

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Publié dans:Viral Immunol
Auteurs principaux: Liu, Jianyun, Gallo, Richard M., Duffy, Carol, Brutkiewicz, Randy R.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031099/
https://ncbi.nlm.nih.gov/pubmed/27327902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2015.0145
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