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STAT3 promotes CD1d-mediated lipid antigen presentation by regulating a critical gene in glycosphingolipid biosynthesis

Cytokines that regulate the immune response signal through the Janus kinase / signal transducer and activation of transcription (JAK/STAT) pathway, but whether this pathway can regulate CD1d-mediated lipid antigen presentation to natural killer T (NKT) cells is unknown. Here, we found that STAT3 pro...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Iyer, Abhirami K, Liu, Jianyun, Gallo, Richard M, Kaplan, Mark H, Brutkiewicz, Randy R
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610633/
https://ncbi.nlm.nih.gov/pubmed/26260288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12521
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