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The Toll‐like receptor 9 signalling pathway regulates MR1‐mediated bacterial antigen presentation in B cells

Mucosal‐associated invariant T (MAIT) cells are conserved T cells that express a semi‐invariant T‐cell receptor (Vα7.2 in humans and Vα19 in mice). The development of MAIT cells requires the antigen‐presenting MHC‐related protein 1 (MR1), as well as commensal bacteria. The mechanisms that regulate t...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Liu, Jianyun, Brutkiewicz, Randy R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588774/
https://ncbi.nlm.nih.gov/pubmed/28518215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12759
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