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Reduced Efficacy of Anti-Aβ Immunotherapy in a Mouse Model of Amyloid Deposition and Vascular Cognitive Impairment Comorbidity

Vascular cognitive impairment and dementia (VCID) is the second most common form of dementia behind Alzheimer's disease (AD). It is estimated that 40% of AD patients also have some form of VCID. One promising therapeutic for AD is anti-Aβ immunotherapy, which uses antibodies against Aβ to clear...

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Publicado en:J Neurosci
Autores principales: Weekman, Erica M., Sudduth, Tiffany L., Caverly, Carly N., Kopper, Timothy J., Phillips, Oliver W., Powell, Dave K., Wilcock, Donna M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030351/
https://ncbi.nlm.nih.gov/pubmed/27656027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1762-16.2016
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