Time course of neuropathological events in hyperhomocysteinemic amyloid depositing mice reveals early neuroinflammatory changes that precede amyloid changes and cerebrovascular events

BACKGROUND: Vascular contributions to cognitive impairment and dementia (VCID) are the second leading cause of dementia behind only Alzheimer’s disease (AD); however, VCID is commonly found as a co-morbidity with sporadic AD. We have previously established a mouse model of VCID by inducing hyperhomo...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Weekman, Erica M., Sudduth, Tiffany L., Price, Brittani R., Woolums, Abigail E., Hawthorne, Danielle, Seaks, Charles E., Wilcock, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6937663/
https://ncbi.nlm.nih.gov/pubmed/31888650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1685-z
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