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Hepatocyte growth factor inhibits hypoxia/reoxygenation-induced activation of xanthine oxidase in endothelial cells through the JAK2 signaling pathway

Vascular endothelial cells (ECs) appear to be one of the primary targets of hypoxia/reoxygenation (H/R) injury. In our previous study, we demonstrated that hepatocyte growth factor (HGF) exhibited a protective effect in cardiac microvascular endothelial cells (CMECs) subjected to H/R by inhibiting x...

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Bibliographic Details
Published in:Int J Mol Med
Main Authors: Zhang, Ying Qian, Hu, Shun Ying, Chen, Yun Dai, Guo, Ming Zhou, Wang, Shan
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029971/
https://ncbi.nlm.nih.gov/pubmed/27573711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2708
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