RNA duplex map in living cells reveals higher order transcriptome structure

RNA has the intrinsic property to base pair, forming complex structures fundamental to its diverse functions. Here we develop PARIS, a method based on reversible psoralen-crosslinking for global mapping of RNA duplexes with near base-pair resolution in living cells. PARIS analysis in three human and...

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Dades bibliogràfiques
Publicat a:Cell
Autors principals: Lu, Zhipeng, Zhang, Qiangfeng Cliff, Lee, Byron, Flynn, Ryan A., Smith, Martin A., Robinson, James T., Davidovich, Chen, Gooding, Anne R., Goodrich, Karen J., Mattick, John S., Mesirov, Jill P., Cech, Thomas R., Chang, Howard Y.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029792/
https://ncbi.nlm.nih.gov/pubmed/27180905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.028
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