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RNA Seeds Higher Order Assembly of FUS Protein
The abundant nuclear RNA-binding protein FUS binds the CTD of RNA polymerase II in an RNA-dependent manner, affecting Ser2 phosphorylation and transcription. Here we examine the mechanism of this process and find that RNA binding nucleates the formation of higher order FUS RNP assemblies that bind t...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925748/ https://ncbi.nlm.nih.gov/pubmed/24268778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.11.017 |
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