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How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA
The POT1-TPP1 heterodimer, the major telomere-specific single-stranded DNA-binding protein in mammalian cells, protects chromosome ends and contributes to the regulation of telomerase. The recent discovery of telomeric RNA raises the question of how POT1 faithfully binds telomeric ssDNA and avoids i...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796979/ https://ncbi.nlm.nih.gov/pubmed/20080730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911099107 |
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