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Multiple POT1-TPP1 Proteins Coat and Compact Long Telomeric Single-stranded DNA
Telomeres are nucleoprotein complexes that cap and protect the ends of linear chromosomes. In humans, telomeres end in 50 – 300 nucleotides of G-rich single-stranded DNA (ssDNA) overhangs. Protection of telomeres 1 (POT1) binds with nanomolar affinity to the ssDNA overhangs and forms a dimer with an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157753/ https://ncbi.nlm.nih.gov/pubmed/21596049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.049 |
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