Targeting the epigenetic readers in Ewing Sarcoma inhibits the oncogenic transcription factor EWS/Fli1

Ewing Sarcoma is a rare bone and soft tissue malignancy affecting children and young adults. Chromosomal translocations in this cancer produce fusion oncogenes as characteristic molecular signatures of the disease. The most common case is the translocation t (11; 22) (q24;q12) which yields the EWS-F...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jacques, Camille, Lamoureux, François, Baud’huin, Marc, Calleja, Lidia Rodriguez, Quillard, Thibaut, Amiaud, Jérôme, Tirode, Franck, Rédini, Françoise, Bradner, James E., Heymann, Dominique, Ory, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029689/
https://ncbi.nlm.nih.gov/pubmed/27006472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8214
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