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Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis
Ewing sarcoma is the second most frequent pediatric bone tumor. In most of the patients, a chromosomal translocation leads to the expression of the EWS-FLI1 chimeric transcription factor that is the major oncogene in this pathology. Relative genetic simplicity of Ewing sarcoma makes it particularly...
Tallennettuna:
| Päätekijät: | , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799442/ https://ncbi.nlm.nih.gov/pubmed/23935076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt678 |
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