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Alteration of Mesodermal Cell Differentiation by EWS/FLI-1, the Oncogene Implicated in Ewing's Sarcoma

The chimeric fusion gene EWS/FLI-1 is detected in most cases of Ewing's sarcoma (ES), the second most common malignant bone tumor of childhood. Although 80% of ES tumors develop in skeletal sites, the remainder can arise in almost any soft tissue location. The lineage of the cell developing the...

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Detalhes bibliográficos
Main Authors: Eliazer, Susan, Spencer, Jeffrey, Ye, Dan, Olson, Eric, Ilaria, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151529/
https://ncbi.nlm.nih.gov/pubmed/12509448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.2.482-492.2003
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