Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth

We hypothesized that tumor-associated macrophages (TAMs) are controlled by the diffusible gas carbon monoxide (CO). We demonstrate that induction of apoptosis in lung tumors treated with low doses of CO is associated with increased CD86 expression and activation of mitogen-activated protein kinase (...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nemeth, Zsuzsanna, Csizmadia, Eva, Vikstrom, Lisa, Li, Mailin, Bisht, Kavita, Feizi, Alborz, Otterbein, Sherrie, Zuckerbraun, Brian, Costa, Daniel B., Pandolfi, Pier Paolo, Fillinger, Janos, Döme, Balazs, Otterbein, Leo E., Wegiel, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029674/
https://ncbi.nlm.nih.gov/pubmed/26993595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8081
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