Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth

We hypothesized that tumor-associated macrophages (TAMs) are controlled by the diffusible gas carbon monoxide (CO). We demonstrate that induction of apoptosis in lung tumors treated with low doses of CO is associated with increased CD86 expression and activation of mitogen-activated protein kinase (...

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Pubblicato in:Oncotarget
Autori principali: Nemeth, Zsuzsanna, Csizmadia, Eva, Vikstrom, Lisa, Li, Mailin, Bisht, Kavita, Feizi, Alborz, Otterbein, Sherrie, Zuckerbraun, Brian, Costa, Daniel B., Pandolfi, Pier Paolo, Fillinger, Janos, Döme, Balazs, Otterbein, Leo E., Wegiel, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029674/
https://ncbi.nlm.nih.gov/pubmed/26993595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8081
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