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Heme oxygenase-1 and carbon monoxide modulate DNA repair through ataxia-telangiectasia mutated (ATM) protein

Stability and repair of DNA is of principal importance in cell survival. Heme oxygenase-1 (HO-1; Hmox1) is critical in maintaining cellular homeostasis, in large part through its ability to generate CO, but neither molecule has been studied in the setting of DNA damage. Naïve Hmox1(−/−) mice exhibit...

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Bibliografiset tiedot
Päätekijät: Otterbein, Leo E., Hedblom, Andreas, Harris, Clair, Csizmadia, Eva, Gallo, David, Wegiel, Barbara
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167547/
https://ncbi.nlm.nih.gov/pubmed/21849621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102295108
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