Heme oxygenase-1 derived carbon monoxide permits maturation of myeloid cells

Critical functions of the immune system are maintained by the ability of myeloid progenitors to differentiate and mature into macrophages. We hypothesized that the cytoprotective gas molecule carbon monoxide (CO), generated endogenously by heme oxygenases (HO), promotes differentiation of progenitor...

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Detalhes bibliográficos
Main Authors: Wegiel, B, Hedblom, A, Li, M, Gallo, D, Csizmadia, E, Harris, C, Nemeth, Z, Zuckerbraun, B S, Soares, M, Persson, J L, Otterbein, L E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973235/
https://ncbi.nlm.nih.gov/pubmed/24651442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.97
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