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Heme oxygenase-1 derived carbon monoxide permits maturation of myeloid cells

Critical functions of the immune system are maintained by the ability of myeloid progenitors to differentiate and mature into macrophages. We hypothesized that the cytoprotective gas molecule carbon monoxide (CO), generated endogenously by heme oxygenases (HO), promotes differentiation of progenitor...

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Dettagli Bibliografici
Autori principali: Wegiel, B, Hedblom, A, Li, M, Gallo, D, Csizmadia, E, Harris, C, Nemeth, Z, Zuckerbraun, B S, Soares, M, Persson, J L, Otterbein, L E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973235/
https://ncbi.nlm.nih.gov/pubmed/24651442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.97
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