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Heme detoxification by heme oxygenase-1 reinstates proliferative and immune balances upon genotoxic tissue injury

Phenotypic changes of myeloid cells are critical to the regulation of premature aging, development of cancer, and responses to infection. Heme metabolism has a fundamental role in the regulation of myeloid cell function and activity. Here, we show that deletion of heme oxygenase-1 (HO-1), an enzyme...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hedblom, Andreas, Hejazi, Seyed M., Canesin, Giacomo, Choudhury, Reeham, Hanafy, Khalid A., Csizmadia, Eva, Persson, Jenny L., Wegiel, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347604/
https://ncbi.nlm.nih.gov/pubmed/30683864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1342-6
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