Adaptive Potential of the Heme Oxygenase/Carbon Monoxide Pathway During Hypoxia

Heme oxygenase (HO) enzymes catalyze heme into biliverdin, releasing carbon monoxide (CO) and iron into circulation. These byproducts of heme degradation can have potent cytoprotective effects in the face of stressors such as hypoxia and ischemia-reperfusion events. The potential for exogenous use o...

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Foilsithe in:Front Physiol
Main Authors: Tift, Michael S., Alves de Souza, Rodrigo W., Weber, Janick, Heinrich, Erica C., Villafuerte, Francisco C., Malhotra, Atul, Otterbein, Leo E., Simonson, Tatum S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Physiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387684/
https://ncbi.nlm.nih.gov/pubmed/32792988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00886
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