Adaptive Potential of the Heme Oxygenase/Carbon Monoxide Pathway During Hypoxia

Heme oxygenase (HO) enzymes catalyze heme into biliverdin, releasing carbon monoxide (CO) and iron into circulation. These byproducts of heme degradation can have potent cytoprotective effects in the face of stressors such as hypoxia and ischemia-reperfusion events. The potential for exogenous use o...

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Dettagli Bibliografici
Pubblicato in:Front Physiol
Autori principali: Tift, Michael S., Alves de Souza, Rodrigo W., Weber, Janick, Heinrich, Erica C., Villafuerte, Francisco C., Malhotra, Atul, Otterbein, Leo E., Simonson, Tatum S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387684/
https://ncbi.nlm.nih.gov/pubmed/32792988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00886
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