Adaptive Potential of the Heme Oxygenase/Carbon Monoxide Pathway During Hypoxia

Heme oxygenase (HO) enzymes catalyze heme into biliverdin, releasing carbon monoxide (CO) and iron into circulation. These byproducts of heme degradation can have potent cytoprotective effects in the face of stressors such as hypoxia and ischemia-reperfusion events. The potential for exogenous use o...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Tift, Michael S., Alves de Souza, Rodrigo W., Weber, Janick, Heinrich, Erica C., Villafuerte, Francisco C., Malhotra, Atul, Otterbein, Leo E., Simonson, Tatum S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387684/
https://ncbi.nlm.nih.gov/pubmed/32792988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00886
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