IMB-6G, a novel N-substituted sophoridinic acid derivative, induces endoplasmic reticulum stress-mediated apoptosis via activation of IRE1α and PERK signaling

Sophoridinic acid derivatives have received considerable attentions for their potencies in cancer therapy. IMB-6G is a novel N-substituted sophoridinic acid derivative with potent cytotoxicity against tumor cells. In the present study, we explored the antitumor abilities of IMB-6G in human hepatocel...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Na, Bi, Chongwen, Liu, Lu, Dou, Yueying, Tang, Sheng, Pang, Weiqiang, Deng, Hongbin, Song, Danqing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029669/
https://ncbi.nlm.nih.gov/pubmed/27009865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8184
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