Activation of autophagy flux by metformin downregulates cellular FLICE–like inhibitory protein and enhances TRAIL- induced apoptosis

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily. TRAIL is regarded as one of the most promising anticancer agents, because it can destruct cancer cells without showing any toxicity to normal cells. Metformin is an anti-diabetic drug with antic...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Nazim, Uddin MD, Moon, Ji-Hong, Lee, Ju-Hee, Lee, You-Jin, Seol, Jae-Won, Eo, Seong-Kug, Lee, John-Hwa, Park, Sang-Youel
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029640/
https://ncbi.nlm.nih.gov/pubmed/26992204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8048
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars