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Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells

An unusual molecular structure of the prion protein, PrPsc is found only in mammals with transmissible prion diseases. Prion protein stands for either the infectious pathogen itself or a main component of it. Recent studies suggest that autophagy is one of the major functions that keep cells alive a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Moon, Ji-Hong, Lee, Ju-Hee, Nazim, Uddin MD, Lee, You-Jin, Seol, Jae-Won, Eo, Seong-Kug, Lee, John-hwa, Park, Sang-Youel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058658/
https://ncbi.nlm.nih.gov/pubmed/27102156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8802
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