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Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells

An unusual molecular structure of the prion protein, PrPsc is found only in mammals with transmissible prion diseases. Prion protein stands for either the infectious pathogen itself or a main component of it. Recent studies suggest that autophagy is one of the major functions that keep cells alive a...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Moon, Ji-Hong, Lee, Ju-Hee, Nazim, Uddin MD, Lee, You-Jin, Seol, Jae-Won, Eo, Seong-Kug, Lee, John-hwa, Park, Sang-Youel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058658/
https://ncbi.nlm.nih.gov/pubmed/27102156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8802
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