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Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells

An unusual molecular structure of the prion protein, PrPsc is found only in mammals with transmissible prion diseases. Prion protein stands for either the infectious pathogen itself or a main component of it. Recent studies suggest that autophagy is one of the major functions that keep cells alive a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Moon, Ji-Hong, Lee, Ju-Hee, Nazim, Uddin MD, Lee, You-Jin, Seol, Jae-Won, Eo, Seong-Kug, Lee, John-hwa, Park, Sang-Youel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058658/
https://ncbi.nlm.nih.gov/pubmed/27102156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8802
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