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Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells

An unusual molecular structure of the prion protein, PrPsc is found only in mammals with transmissible prion diseases. Prion protein stands for either the infectious pathogen itself or a main component of it. Recent studies suggest that autophagy is one of the major functions that keep cells alive a...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Moon, Ji-Hong, Lee, Ju-Hee, Nazim, Uddin MD, Lee, You-Jin, Seol, Jae-Won, Eo, Seong-Kug, Lee, John-hwa, Park, Sang-Youel
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058658/
https://ncbi.nlm.nih.gov/pubmed/27102156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8802
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