Ophiopogonin B sensitizes TRAIL-induced apoptosis through activation of autophagy flux and downregulates cellular FLICE-like inhibitory protein

Tumor necrosis factor related apoptosis-inducing ligand (TRAIL), a type II transmembrane protein, belongs to the TNF superfamily. Compared to other family members, TRAIL is a promising anti-cancer agent that can selectively induce apoptosis of various types of transformed cells and xenografts, with...

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Foilsithe in:Oncotarget
Main Authors: Nazim, Uddin MD., Jeong, Jae-Kyo, Park, Sang-Youel
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2017
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790529/
https://ncbi.nlm.nih.gov/pubmed/29423112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23647
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