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Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL-induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is well known as a transmembrane cytokine and has been proposed as one of the most effective anti-cancer therapeutic agents, owing to its efficiency to selectively induce cell death in a variety of tumor cells. Suppression of autophagy...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Med Rep
Main Authors: Nazim, Uddin Md, Yin, Honghua, Park, Sang-Youel
פורמט: Artigo
שפה:Inglês
יצא לאור: D.A. Spandidos 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6323218/
https://ncbi.nlm.nih.gov/pubmed/30569150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9757
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