Activation of autophagy flux by metformin downregulates cellular FLICE–like inhibitory protein and enhances TRAIL- induced apoptosis

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily. TRAIL is regarded as one of the most promising anticancer agents, because it can destruct cancer cells without showing any toxicity to normal cells. Metformin is an anti-diabetic drug with antic...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Nazim, Uddin MD, Moon, Ji-Hong, Lee, Ju-Hee, Lee, You-Jin, Seol, Jae-Won, Eo, Seong-Kug, Lee, John-Hwa, Park, Sang-Youel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029640/
https://ncbi.nlm.nih.gov/pubmed/26992204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8048
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi