[(64)Cu]‐labelled trastuzumab: optimisation of labelling by DOTA and NODAGA conjugation and initial evaluation in mice

The human epidermal growth factor receptor‐2 (HER2) is overexpressed in 20–30% of all breast cancer cases, leading to increased cell proliferation, growth and migration. The monoclonal antibody, trastuzumab, binds to HER2 and is used for treatment of HER2‐positive breast cancer. Trastuzumab has prev...

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Spremljeno u:
Bibliografski detalji
Izdano u:J Labelled Comp Radiopharm
Glavni autori: Schjoeth‐Eskesen, Christina, Nielsen, Carsten Haagen, Heissel, Søren, Højrup, Peter, Hansen, Paul Robert, Gillings, Nic, Kjaer, Andreas
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029596/
https://ncbi.nlm.nih.gov/pubmed/25906708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3287
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