[(64)Cu]‐labelled trastuzumab: optimisation of labelling by DOTA and NODAGA conjugation and initial evaluation in mice

The human epidermal growth factor receptor‐2 (HER2) is overexpressed in 20–30% of all breast cancer cases, leading to increased cell proliferation, growth and migration. The monoclonal antibody, trastuzumab, binds to HER2 and is used for treatment of HER2‐positive breast cancer. Trastuzumab has prev...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Labelled Comp Radiopharm
Asıl Yazarlar: Schjoeth‐Eskesen, Christina, Nielsen, Carsten Haagen, Heissel, Søren, Højrup, Peter, Hansen, Paul Robert, Gillings, Nic, Kjaer, Andreas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2015
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029596/
https://ncbi.nlm.nih.gov/pubmed/25906708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3287
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