Targeted modification of mitochondrial ROS production converts high glucose-induced cytotoxicity to cytoprotection: Effects on anesthetic preconditioning

Contradictory reports on the effects of diabetes and hyperglycemia on myocardial infarction range from cytotoxicity to cytoprotection. The study was designed to investigate acute effects of high glucose-driven changes in mitochondrial metabolism and osmolarity on adaptive mechanisms and resistance t...

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Veröffentlicht in:J Cell Physiol
Hauptverfasser: Sedlic, Filip, Muravyeva, Maria, Sepac, Ana, Sedlic, Marija, Williams, Anna Marie, Yang, Meiying, Bai, Xiaowen, Bosnjak, Zeljko J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028252/
https://ncbi.nlm.nih.gov/pubmed/27138089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25413
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