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Dosage Thresholds for AAV2 and AAV8 Photoreceptor Gene Therapy in Monkey

Gene therapy is emerging as a therapeutic modality for treating disorders of the retina. Photoreceptor cells are the primary cell type affected in many inherited diseases of retinal degeneration. Successfully treating these diseases with gene therapy requires the identification of efficient and safe...

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Podrobná bibliografie
Vydáno v:Sci Transl Med
Hlavní autoři: Vandenberghe, Luk H., Bell, Peter, Maguire, Albert M., Cearley, Cassia N., Xiao, Ru, Calcedo, Roberto, Wang, Lili, Castle, Michael J., Maguire, Alexandra C., Grant, Rebecca, Wolfe, John H., Wilson, James M., Bennett, Jean
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027886/
https://ncbi.nlm.nih.gov/pubmed/21697530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002103
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