AAV9 Targets Cone Photoreceptors in the Nonhuman Primate Retina

Transduction of retinal pigment epithelial cells with an adeno-associated viral vector (AAV) based on serotype 2 has partially corrected retinal blindness in Leber congenital amaurosis type 2. However, many applications of gene therapy for retinal blindness rely on the efficient transduction of rod...

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Bibliografiske detaljer
Main Authors: Vandenberghe, Luk H., Bell, Peter, Maguire, Albert M., Xiao, Ru, Hopkins, Tim B., Grant, Rebecca, Bennett, Jean, Wilson, James M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559681/
https://ncbi.nlm.nih.gov/pubmed/23382846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053463
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