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Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction
We present a scalable, integrated strategy for coupled protein and RNA detection from single cells. Our approach leverages the DNA polymerase activity of reverse transcriptase to simultaneously perform proximity extension assays and complementary DNA synthesis in the same reaction. Using the Fluidig...
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出版年: | Genome Biol |
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主要な著者: | , , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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BioMed Central
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5027636/ https://ncbi.nlm.nih.gov/pubmed/27640647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1045-6 |
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