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Independent and inter-dependent immunoregulatory effects of IL-27, IFN-β and IL-10 in the suppression of human Th17 cells and murine EAE

IFN-β, IL-27 and IL-10 have been shown to exert a range of similar immunoregulatory effects in murine and human experimental systems, particularly in Th1 and Th17 mediated models of autoimmune inflammatory disease. In this study we sought to translate some of our previous findings in murine systems...

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Publicat a:J Immunol
Autors principals: Fitzgerald, Denise C., Fonseca-Kelly, Zoe, Cullimore, Melissa L., Safabakhsh, Pegah, Saris, Christiaan J. M., Zhang, Guang-Xian, Rostami, Abdolmohamad
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027611/
https://ncbi.nlm.nih.gov/pubmed/23455508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200141
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