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Independent and inter-dependent immunoregulatory effects of IL-27, IFN-β and IL-10 in the suppression of human Th17 cells and murine EAE

IFN-β, IL-27 and IL-10 have been shown to exert a range of similar immunoregulatory effects in murine and human experimental systems, particularly in Th1 and Th17 mediated models of autoimmune inflammatory disease. In this study we sought to translate some of our previous findings in murine systems...

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Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: Fitzgerald, Denise C., Fonseca-Kelly, Zoe, Cullimore, Melissa L., Safabakhsh, Pegah, Saris, Christiaan J. M., Zhang, Guang-Xian, Rostami, Abdolmohamad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027611/
https://ncbi.nlm.nih.gov/pubmed/23455508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200141
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