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Differential effect of IL-27 on developing versus committed Th17 cells
IL-27 counters the effect of TGF-β+IL-6 on naïve CD4(+) T cells, resulting in near complete inhibition of de novo Th17 development. In contrast, little is known about the effect of IL-27 on already differentiated Th17 cells. A better understanding of how IL-27 regulates these cells is needed to eval...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901918/ https://ncbi.nlm.nih.gov/pubmed/19786534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900735 |
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