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Differential effect of IL-27 on developing versus committed Th17 cells

IL-27 counters the effect of TGF-β+IL-6 on naïve CD4(+) T cells, resulting in near complete inhibition of de novo Th17 development. In contrast, little is known about the effect of IL-27 on already differentiated Th17 cells. A better understanding of how IL-27 regulates these cells is needed to eval...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: El-behi, Mohamed, Ciric, Bogoljub, Yu, Shuo, Zhang, Guang-Xian, Fitzgerald, Denise C., Rostami, Abdolmohamad
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901918/
https://ncbi.nlm.nih.gov/pubmed/19786534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900735
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