The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

Interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) require exposure to IL-23 to become encephalitogenic, but the mechanism by which IL-23 promotes their pathogenicity is not known. Here we found that IL-23 induced production of the cytokine granulocyte macrophage colony-stimulating facto...

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Main Authors: El-Behi, Mohamed, Ciric, Bogoljub, Dai, Hong, Yan, Yaping, Cullimore, Melissa, Safavi, Farinaz, Zhang, Guang-Xian, Dittel, Bonnie N., Rostami, Abdolmohamad
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116521/
https://ncbi.nlm.nih.gov/pubmed/21516111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2031
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