The absence of p53 during Human Cytomegalovirus infection leads to decreased UL53 expression, disrupting UL50 localization to the inner nuclear membrane, and thereby inhibiting capsid nuclear egress

Lignende værker

• Human Cytomegalovirus nuclear egress and secondary envelopment are negatively affected in the absence of cellular p53
  af: Kuan, Man I., et al.
  Udgivet: (2016)
• Human Cytomegalovirus UL50 and UL53 Recruit Viral Protein Kinase UL97, Not Protein Kinase C, for Disruption of Nuclear Lamina and Nuclear Egress in Infected Cells
  af: Sharma, Mayuri, et al.
  Udgivet: (2014)
• Human Cytomegalovirus Nuclear Capsids Associate with the Core Nuclear Egress Complex and the Viral Protein Kinase pUL97
  af: Milbradt, Jens, et al.
  Udgivet: (2018)
• Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation
  af: Häge, Sigrun, et al.
  Udgivet: (2021)
• Human Cytomegalovirus UL97 Phosphorylates the Viral Nuclear Egress Complex
  af: Sharma, Mayuri, et al.
  Udgivet: (2014)