Human Cytomegalovirus nuclear egress and secondary envelopment are negatively affected in the absence of cellular p53

Human Cytomegalovirus (HCMV) infection is compromised in cells lacking p53, a transcription factor that mediates cellular stress responses. In this study we have investigated compromised functional virion production in cells with p53 knocked out (p53KOs). Infectious center assays found most p53KOs r...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Kuan, Man I., O’Dowd, John M., Chughtai, Kamila, Hayman, Ian, Brown, Celeste J., Fortunato, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026618/
https://ncbi.nlm.nih.gov/pubmed/27498410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.07.021
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