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Human Cytomegalovirus UL97 Phosphorylates the Viral Nuclear Egress Complex

Herpesvirus nucleocapsids exit the host cell nucleus in an unusual process known as nuclear egress. The human cytomegalovirus (HCMV) UL97 protein kinase is required for efficient nuclear egress, which can be explained by its phosphorylation of the nuclear lamina component lamin A/C, which disrupts t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sharma, Mayuri, Bender, Brian J., Kamil, Jeremy P., Lye, Ming F., Pesola, Jean M., Reim, Natalia I., Hogle, James M., Coen, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301116/
https://ncbi.nlm.nih.gov/pubmed/25339763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02426-14
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