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Human Cytomegalovirus UL97 Phosphorylates the Viral Nuclear Egress Complex

Herpesvirus nucleocapsids exit the host cell nucleus in an unusual process known as nuclear egress. The human cytomegalovirus (HCMV) UL97 protein kinase is required for efficient nuclear egress, which can be explained by its phosphorylation of the nuclear lamina component lamin A/C, which disrupts t...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Sharma, Mayuri, Bender, Brian J., Kamil, Jeremy P., Lye, Ming F., Pesola, Jean M., Reim, Natalia I., Hogle, James M., Coen, Donald M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301116/
https://ncbi.nlm.nih.gov/pubmed/25339763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02426-14
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