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Perspective: Targeting the JAK/STAT pathway to fight age-related dysfunction
Senescent cells accumulate in a variety of tissues with aging. They can develop a senescence-associated secretory phenotype (SASP) that entails secretion of inflammatory cytokines, chemokines, proteases, and growth factors. These SASP components can alter the microenvironment within tissues and affe...
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| Publicado no: | Pharmacol Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026572/ https://ncbi.nlm.nih.gov/pubmed/27241018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.05.015 |
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