Loading...

The JAK-STAT Pathway at Twenty

We look back on the discoveries that the tyrosine kinases TYK2 and JAK1 and the transcription factors STAT1, STAT2, and IRF9 are required for the cellular response to type I interferons. This initial description of the JAK-STAT pathway led quickly to additional discoveries that type II interferons a...

Full description

Saved in:
Bibliographic Details
Main Authors: Stark, George R., Darnell, James E.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909993/
https://ncbi.nlm.nih.gov/pubmed/22520844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.03.013
Tags: Add Tag
No Tags, Be the first to tag this record!