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The JAK-STAT Pathway at Twenty
We look back on the discoveries that the tyrosine kinases TYK2 and JAK1 and the transcription factors STAT1, STAT2, and IRF9 are required for the cellular response to type I interferons. This initial description of the JAK-STAT pathway led quickly to additional discoveries that type II interferons a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3909993/ https://ncbi.nlm.nih.gov/pubmed/22520844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.03.013 |
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