Oxidative damage and chemokine production dominate days before immune cell infiltration and EAE disease debut

BACKGROUND: Multiple sclerosis is widely accepted as an inflammatory disease. However, studies indicate that degenerative processes in the CNS occur prior to inflammation. In the widely used animal model experimental autoimmune encephalomyelitis (EAE), we investigated the significance of degenerativ...

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Библиографические подробности
Опубликовано в: :J Neuroinflammation
Главные авторы: Hasseldam, Henrik, Rasmussen, Rune Skovgaard, Johansen, Flemming Fryd
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024447/
https://ncbi.nlm.nih.gov/pubmed/27630002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0707-3
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