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The Hypothermic Influence on CHOP and Ero1-α in an Endoplasmic Reticulum Stress Model of Cerebral Ischemia

Hypoxia induced endoplasmic reticulum stress causes accumulation of unfolded proteins in the endoplasmic reticulum and activates the unfolded protein response, resulting in apoptosis through CCAAT-enhancer-binding protein homologous protein (CHOP) activation. In an in vitro and in vivo model of isch...

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Detalhes bibliográficos
Publicado no:Brain Sci
Main Authors: Poone, Gagandip K., Hasseldam, Henrik, Munkholm, Nina, Rasmussen, Rune S., Grønberg, Nina V., Johansen, Flemming F.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493463/
https://ncbi.nlm.nih.gov/pubmed/25989620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci5020178
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