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Oxidative damage and chemokine production dominate days before immune cell infiltration and EAE disease debut

BACKGROUND: Multiple sclerosis is widely accepted as an inflammatory disease. However, studies indicate that degenerative processes in the CNS occur prior to inflammation. In the widely used animal model experimental autoimmune encephalomyelitis (EAE), we investigated the significance of degenerativ...

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Bibliographische Detailangaben
Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Hasseldam, Henrik, Rasmussen, Rune Skovgaard, Johansen, Flemming Fryd
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024447/
https://ncbi.nlm.nih.gov/pubmed/27630002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0707-3
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