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Oxidative damage and chemokine production dominate days before immune cell infiltration and EAE disease debut

BACKGROUND: Multiple sclerosis is widely accepted as an inflammatory disease. However, studies indicate that degenerative processes in the CNS occur prior to inflammation. In the widely used animal model experimental autoimmune encephalomyelitis (EAE), we investigated the significance of degenerativ...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Hasseldam, Henrik, Rasmussen, Rune Skovgaard, Johansen, Flemming Fryd
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024447/
https://ncbi.nlm.nih.gov/pubmed/27630002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0707-3
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